|
Patent Awards:
Method For Producing Purified Tocotrienols
and Tocopherols Using Liquid Chromatography
Inventors:
Lou Bellafiore, Kevin Henretta
Assignee:
TechniKrom, Inc., Evanston, IL
Patent
No.: US 6,395,915 B1
Patent
Date: May 28, 2002
Abstract:
A method separating tocotrienols from tocopherols and the
isomers thereof on a large-scale or commercially feasible
basis. Separation is accomplished using reverse phase partition
liquid chromatography.
The chromatography column is prepared
using a stationary phase comprising a hydrophobic or aromatic
reverse phase chromatography media. The mobile phase consists
of a solvent which is capable of solubilizing the crude stock,
tocotrienols and tocopherols. The chomatography column containing
the stationary and mobile phases is loaded with a crude feed
stock and the tocotrienols, tocopherols and /or isomers thereof
are eluted at a predetermined linear velocity.
|
