TechniKrom Filtration Systems


Built to order pilot to production scale filtration skid systems
Tangential Flow Filtration, Viral Filtration, UF/DF
TFF Systems
  • TFF system includes feed tank, feed pump and required instrumentation
  • Standard or tulip design feed tanks
  • Sanitary positive displacement pump
  • TMP, temperature, flow measurement
  • UV detection of filtrate
  • Conductivity and pH instrumentation
  • ASME BPE 2005 compliant
  • Available with Allen-Bradley PLC control with integrated OIT or external PC
  • 21CFR Part 11 capable software
  • Connect into plant wide control system
  • Real time data logging of TMP, conductivity, pH, temperature, volume, UV
  • Complete IQ/OQ and GAMP-4 execution and documentation available for turnkey operation

Integrated process control overview with intuitive user interface
Viral Filtration Systems
  • VF system can be used with Asahi Planova™ virus removal filters
  • Includes fully steam sterilizable design
  • Sterility validation using integrated F0 calculator
  • Automated control includes:
    • Pressurization test
    • SIP with F0 results for each cycle
    • Filter pre-wash
    • Filtration
    • Post-rinse
    • Drain
    • Post water rinse
    • Water drain
    • CIP
    • Neutralization


Configurable alarm settings



Neutralization step editor
     

Filtration control settings
Customizable clean-in-place protocol


Comprehensive IQ/OQ Validation Documentation
Best in the industry, well-organized and comprehensive
TechniKrom designs, builds and tests all equipment in accordance with FDA, ISPE GAMP-4, ASME-BPE, UL, and international codes (e.g. ATEX). A project engineering manager coordinates each project and works with you directly, from the design phase to the final installation and training.

Comprehensive IQ/OQ validation package includes TechniKrom's world-class validation
protocol and system documentation. The validation package provides detailed testing
reports on all IQ/OQ validation procedures (over 200 tests) as well as all component
manuals, test certificates and documentation. Our clients have been able to cut validation
times from months to days using our validation package.


Warranty and Technical Support
  • One year extendable warranty, service contracts and 24 hour response time means peace of mind and fast support when you need it.
  • Our partner companies throughout Europe and Asia assist with overseas tech support Additional Biopharmaceutical Products:
  • Chromatography skids with Adaptive PAT™
  • IBD™ in-line buffer dilution skids with Adaptive PAT™
  • Adaptive PAT™ pH adjustment skids
  • Dynamic axial compression bioprocess columns
  • Dynamic axial Compression HPLC columns
  • AGPTS gold particle post-use integrity test systems for Asahi Planova™ virus removal filters
  • TFF skids as well as VF skids to support Asahi Planova™ virus removal filters

About TechniKrom
TechniKrom is a privately held, diversified engineering and qualification firm that provides technologically advanced blending, synthesis, filtration and purification equipment, products and services to the Biopharmaceutical, Pharmaceutical, and Nutraceutical Industries worldwide that permit the lowest cost of production and highest innate product quality, especially in cGMP regulated environments. TechniKrom promotes the implementation of Manufacturing Science in biopharmaceutical manufacturing facilities. For additional information, visit www.technikrom.com.